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Stroke Rehabilitation Using BCI Technology

June 19, 2019


The purpose of this clinical trial is to see if functional muscle stimulation, directed by electroencephalogram (EEG) output, can increase the extent of stroke recovery on behavioral measures. Also, it hopes to promote the brain’s ability to reorganize itself (plasticity) as measured by functional magnetic resonance imaging (fMRI).


Study Information

This is an interventional, randomized, parallel assignment with the primary purpose of stroke treatment. There is an estimated 192 participants. The study began in June 2010 and is expected to be completed by June 2022.


Inclusion Criteria


  • All sexes, ages 55 to 85 years old
  • New-onset ischemic stroke 12 months prior – chronic time frame
  • Right hand dominant – affected arm
  • Mild to moderate unilateral upper extremity impairment or severe unilateral upper extremity impairment
  • No upper extremity injury or conditions that limited use prior to the stroke
  • Must be able to provide informed consent on their own behalf


Exclusion Criteria


  • Contraindications to MRI
  • Allergies to electrode gel, surgical tape, or metals
  • Pregnancy
  • Current treatment for infectious disease
  • Active oral lesions or inflammation



You may participate in this study at the University of Wisconsin in Madison, Wisconsin, United States, 53706. If you have any questions or concerns you may contact Theresa Kang, BS at 608-262-4033 or at



This study is sponsored by the University of Wisconsin, Madison and collaborated by the National Institute of Neurological Disorders and Stroke (NINDS). The Principal Investigator is Vivek Prabhakaran, MD, PhD of the University of Wisconsin, Madison.

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