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Constraint Induced Movement Therapy Post Stroke

June 19, 2019


This is a 6 week study with three assessments to compare the effect of constraint induced movement therapy (CIMT) vs. treadmill training only on walking function in individuals post-stroke. Participants will be assigned to either the CIMT or treadmill training only groups at the initial test. After the first test, individuals from the 2 groups will undergo intensive walking training. Training will be performed 3 times per week for 6 weeks for 45 minutes each visit.


Study Information

This is an interventional, randomized, single-blind, parallel assignment with the primary purpose of treatment. There is an estimated 36 participants. The study began on August 14, 2017 and is estimated to be completed by July 30, 2020.


Inclusion Criteria


  • All sexes, ages between 21 and 75 years
  • History of unilateral, supratentorial, ischemic or hemorrhagic stroke
  • No prior stroke;
  • Demonstration of impaired walking function (self-selected walking speed ≤ 0.80 m/s);
  • Able to stand and walk (>10 meters) without physical assistance


Exclusion Criteria


  • Significant cardiorespiratory/metabolic disease
  • Other neurological or orthopedic injury that impairs walking ability
  • Scores on the mini mental status examination < 24
  • Stroke of the brainstem or cerebellar lesions
  • Uncontrolled hypertension (systolic > 200 mm Hg, diastolic > 110 mm Hg)
  • Botox injection within 6 months of starting the study



You may participate in this clinical trial at Abilitylab in Chicago, Illinois, United States, 60611. If you have any questions or concerns, please contact Weena Dee, PT at 312-238-7503 or at



This study is sponsored by Shirley Ryan AbilityLAb with Ming Wu, PhD, as the Principal Investigator.

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